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Long non-coding RNA PVT1 enhances doxorubicin resistance in breast cancer cells by inhibiting the binding of Keap1 to NRF2, thereby preventing NRF2 protein degradation

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Some studies [55, 56, 57] showed that each catalase tetramer has four tightly bound NADPH molecules that appear to be important only to protect the enzyme against inactivation by its own substrate (H 2 O 2 ), and are not essential for its catalytic activity