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Divergent effects of glutathione depletion on isocitrate dehydrogenase 1 and the pentose phosphate pathway in hamster liver - Jin - 2020 - Physiological Reports - Wiley Online Library

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When NNMT is active, it methylates nicotinamide (a form of vitamin B3), making it unavailable for conversion into NAD⁺ — a crucial molecule for energy production and cellular repair