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Crujeiras, Pissios, Moreno-Navarrete, and colleagues, writing in Molecular Nutrition and Food Research in 2018, identified an epigenetic signature in human adipose tissue linked to NNMT gene expression, reinforcing the idea that the methylation axis is a live variable in human fat biology rather than a rodent-only phenomenon

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Investigation of DNICs, GSTp, and MRP1 as an effective storage and release mechanism for NO and iron in the SN may be useful to discover the elements at work in the balance of homeostasis versus oxidative stress leading to neurodegeneration