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Positively charged or N-CQDs interact electrostatically with the negatively charged bacterial membranes (lipopolysaccharides, lipoteichoic acids), leading to enhanced bacterial adhesion and antibacterial activity [123]

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The SN holds a pivotal role in PD and is divided into two distinct anatomical parts, the pars compacta (SNpc) containing DAergic neurons and the pars reticulata (SNpr) containing GABAergic neurons