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Detailed structure–activity relationship analyses indicate that lengthening or shortening this linker impairs HDAC affinity, whereas modifications within the aromatic fragment (phenyl-ring substitution and the introduction of heteroaromatics) can be used to modulate selectivity toward individual class I/II HDAC isoforms [197]

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Reduced glutathione (GSH) acts as a hydrogen donor in the detoxification of hydrogen peroxide