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This compound's potential research applications extend beyond direct MAPK/ERK modulation

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A combination of in situ rat/mouse intestinal perfusion model along with in vitro intestinal/hepatic microsomes and Caco-2 cell transport studies demonstrated that enteric recycling plays an important role in disposition of various flavonoids, owing to their extensive glucuronidation in intestine and excretion of these glucuronides in gut lumen (Chen et al., 2003a