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doi: 10.1016/j.ejphar.2024.176724 4

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Upon catalysis of COXs, dihomo-γ-linolenic acid (DGLA) and arachidonic acid (AA) can be oxidized by radical-mediated lipid peroxidation and produce prostaglandins, which linking the lipid peroxidation directly to inflammation and apoptotic processes [32,33,34]