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Hypoxia differentially regulates arterial and venous smooth muscle cell proliferation via PDGFR-beta and VEGFR-2 expression
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A preliminary study evaluating diabetic peripheral neuropathy has demonstrated that targeted supplementation with these active B-vitamins (along with pyridoxal 5'-phosphate) can actually increase epidermal nerve fiber density, meaning the nerves physically begin to regrow and heal, leading to a reduction in pain and paresthesia
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